completed Assessment
Virtual Opioid Use Disorder Solutions
Assessment Released
Last Updated
September 16, 2025
Conditions
Opioid Use Disorder
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PHTI assessed virtual opioid use disorder (OUD) solutions that aim to improve treatment retention and expand access to medication-based care.
Area overview
Opioid use disorder is a significant public health crisis, affecting more than 9 million adults across the United States and contributing to approximately 80,000 deaths from overdose each year. The U.S. spends $111 billion annually on direct healthcare costs for OUD.
Despite the availability of highly effective medications, only 25% of adults in need of OUD treatment receive a medication-based intervention. Individuals with OUD face significant barriers to receiving medications for opioid use disorder (MOUD) based treatment, including limited provider availability, onerous and fragmented care requirements, medication availability, and societal stigma.
Virtual OUD solutions include medication-focused solutions that offer virtual prescribing with optional therapy and peer support, as well as digital wraparound solutions that complement existing treatment programs with services like contingency management and care navigation. These solutions aim to improve treatment retention and expand access to MOUD treatment.
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Virtual Opioid Use Disorder Solutions
Released September 16, 2025
September 16, 2025
Executive SummarySeptember 16, 2025
Patient GuideSeptember 16, 2025
Overview for PolicymakersSeptember 16, 2025
AppendicesSeptember 16, 2025
Data SupplementReport contributors and reviewers provided important expertise and insight throughout our process. Those who directly contributed to the report have no relevant conflicts of interest to disclose.
Summary of findings
PHTI’s evaluation indicates that virtual solutions for opioid use disorder are as effective as usual, medication-based treatment and can help people stay on treatment slightly longer—an average of 13 more days over six months. However, despite growing investment and adoption, there is no clear evidence that these digital solutions have meaningfully reduced the overall cost of care or expanded participation in OUD treatment.
Medication-focused solutions may be substituted for usual care with comparable or slightly lower spending but show no substantial improvements in clinical outcomes or access expansion. Digital wraparound solutions increase net spending for purchasers because solution prices exceed avoided healthcare costs.

Guidance & considerations for stakeholders
- Advance evidence generation to demonstrate which aspects of virtual OUD solutions are improving treatment retention and for which populations.
- Expand access by focusing on patient acquisition and engagement to bring a broader range of patients into MOUD treatment and keep them in treatment longer.
- Improve care coordination by integrating virtual OUD solutions more effectively into the healthcare delivery system.
- Leverage opioid settlement funds for OUD support services and evidence-based approaches to OUD treatment.
- Expand the availability and uptake of MOUDs by promoting comprehensive coverage and addressing access barriers to long-acting formulations such as injectable buprenorphine and naltrexone.
- Modernize federal and state policy by finalizing Drug Enforcement Administration (DEA) teleprescribing rules, expanding licensure flexibilities, and investing in rigorous evaluations of digital OUD models and support services tools.
Why assess virtual opioid use disorder solutions?
- OUD affects more than 9 million adults across the United States and contributes to approximately 80,000 overdose deaths annually
- The U.S. spends $111 billion annually on direct healthcare costs for people with OUD, plus an additional $52 billion on related criminal justice costs
- Only one in four adults with OUD who would benefit from medication-based treatment receive it, despite proven medication effectiveness
- More than 75% of employers say they have employees affected by opioid use, with one-third feeling unprepared to help manage the condition
- Virtual OUD solutions have attracted significant investment as potential alternatives to traditional in-person treatment models
- The CDC estimates that of those who do not receive treatment, 95% don’t believe they need treatment, highlighting the opportunity for innovation in patient engagement and treatment initiation
- Employers are seeking solutions for workforce populations affected by OUD, particularly in industrial, construction, and transportation sectors
- Policymakers are modernizing teleprescribing policies at federal and state levels to support virtual care adoption
- Public health agencies are exploring how to leverage opioid settlement funds for evidence-based virtual treatment approaches
Additional resources
February 2025
A systematic literature review of digital health technologies for substance use disorderInternational prospective register of systematic reviews (PROSPERO), National Institute for Health and Care Research
Contact
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Read an overview of our assessment Approach and Framework
View assessment frameworkRelated news
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Sep 18, 2025News Coverage
Axios
Virtual opioid treatment doesn’t deliver major savings, report says
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Sep 16, 2025News Coverage
Endpoints News
Which digital health tools are worth the cost?
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Sep 16, 2025News Coverage
Fierce Healthcare
Virtual solutions for opioid use disorder can substitute for in-person care but don’t increase access
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Sep 16, 2025Announcement
Virtual Opioid Use Disorder Solutions Are as Effective as Usual Care, but Only Slightly Improve Retention
Independent evaluation from the Peterson Health Technology Institute also calls for virtual solutions to focus more on expanding access to treatment
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Mar 6, 2025News Coverage
Fierce Healthcare
Peterson Health Technology Institute to evaluate efficacy of virtual opioid use disorder programs
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Mar 5, 2025Announcement
Virtual Programs to Treat Opioid Use Disorder Will Undergo Independent Evaluation
Peterson Health Technology Institute to assess the clinical and economic impact of virtual programs that care for people with opioid use disorder to inform payers, providers, and patients
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